Insulin Receptor Trafficking: Consequences for Insulin Sensitivity and Diabetes
نویسندگان
چکیده
منابع مشابه
Insulin sensitivity in diabetes mellitus.
While the invention of insulin has brought an epoch-making pro gress in the treatment of diabetes mellitus,1) insulin resistance in this disease is reported to be on the increase. Accordingly, there is much literature in which classification of diabetes mellitus has been tried from insulin sensitivity.2) Falta and his associates have done a great deal in this line; for ex ample, insulin toleran...
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Objective(s): Diabetes mellitus has been suggested to be the most common metabolic disorder associated with magnesium deficiency. This study aimed to investigate the effects and mechanisms of magnesium supplementation on insulin receptor activity in elderly type 2 diabetes using a rat model and to provide experimental evidence for insulin resistance improvement by magn...
متن کاملSex hormones, insulin sensitivity, and diabetes mellitus.
Sex differences and the role of gonadal hormones in modulating insulin sensitivity and glucose tolerance are of increasing interest and importance because of the increasing prevalence of type 2 diabetes mellitus and the metabolic abnormalities associated with aging. Body composition is closely associated with insulin sensitivity, and increased body fat, particularly in the visceral compartment,...
متن کاملEndogenous insulin and insulin sensitivity
Results There was a significant inverse correlation between forearm blood flow and insulin sensitivity (r="0·67, P=0·03), patients with lesser degrees of insulin sensitivity having the greater forearm blood flows. There was no correlation with the other haemodynamic or neurohumoral parameters. Patients with greater insulin resistance tended to have higher circulating endogenous insulin levels, ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2019
ISSN: 1422-0067
DOI: 10.3390/ijms20205007